Sticking to PIP2

Effect of colloidal Particles associated with the liquid bridge in sticking during drying in Superheated Steam

It is very important in the design of a drying system is to evaluate sticking behaviour of the materials goes under drying. A new approach to the sticking issue is applied in this study by carrying out a sticking test for the liquid associated with the materials under study. It was found that the liquid bridge is responsible of the initial sticking of the materials to the contact surface and th...

Sticking with Carrots and Sticks (Sticking Points Aside): A Response to Ventakapuram, Goldberg, and Forrow

Mathematical Modeling of the Differential Sticking Coefficient of Clay Drilling Fluids

The main objective of this work is to propose a mathematical model for the differential sticking coefficient of clayey drilling fluids with a lubricant as an additive and evaluate the influence of differential pressure and lubricant content on filter cake thickness and permeability. Tests were carried out on fluids composed of water and 4.86% of active bentonite clay prepared in Hamilton Beach ...

Inhibition of transient receptor potential A1 channel by phosphatidylinositol-4,5-bisphosphate.

Membrane phosphatidylinositol-4,5-bisphosphate (PIP2) is critical for the function of many transient receptor potential (TRP) ion channels. The role of PIP2 in TRPA1 function is not well known. The effect of PIP2 on TRPA1 was investigated by direct application of PIP2 and by using polylysine and PIP2 antibody that sequester PIP2. In inside-out patches from HeLa cells expressing mouse TRPA1, pol...

HERG K(+) channel activity is regulated by changes in phosphatidyl inositol 4,5-bisphosphate.

Autonomic stimulation controls heart rate and myocardial excitability and may underlie the precipitation of both acquired and hereditary arrhythmias. Changes in phosphatidyl inositol bisphosphate (PIP2) concentration results from activation of several muscarinic and adrenergic receptors. We sought to investigate whether PIP2 changes could alter HERG K(+) channel activity in a manner similar to ...

CAPS and Munc13 utilize distinct PIP2-linked mechanisms to promote vesicle exocytosis

Phosphoinositides provide compartment-specific signals for membrane trafficking. Plasma membrane phosphatidylinositol 4,5-bisphosphate (PIP2) is required for Ca(2+)-triggered vesicle exocytosis, but whether vesicles fuse into PIP2-rich membrane domains in live cells and whether PIP2 is metabolized during Ca(2+)-triggered fusion were unknown. Ca(2+)-dependent activator protein in secretion 1 (CA...